RT Journal Article
T1 Real-Time Wireless Platform for In Vivo Monitoring of Bone Regeneration
A1 Blázquez Carmona, Pablo
A1 Sánchez Raya, Manuel
A1 Mora Macías, Juan
A1 Gómez Galán, Juan Antonio
AB For the monitoring of bone regeneration processes, the instrumentation of the fixationis an increasingly common technique to indirectly measure the evolution of bone formationinstead of ex vivo measurements or traditional in vivo techniques, such as X-ray or visual review.A versatile instrumented external fixator capable of adapting to multiple bone regeneration processeswas designed, as well as a wireless acquisition system for the data collection. The design andimplementation of the overall architecture of such a system is described in this work, includingthe hardware, firmware, and mechanical components. The measurements are conditioned andsubsequently sent to a PC via wireless communication to be in vivo displayed and analyzed usinga developed real-time monitoring application. Moreover, a model for the in vivo estimation of thebone callus stiffness from collected data was defined. This model was validated in vitro using elasticsprings, reporting promising results with respect to previous equipment, with average errors anduncertainties below 6.7% and 14.04%. The devices were also validated in vivo performing a bonelengthening treatment on a sheep metatarsus. The resulting system allowed the in vivo mechanicalcharacterization of the bone callus during experimentation, providing a low-cost, simple, and highlyreliable solution.
PB MDPI
SN 1424-8220
YR 2020
FD 2020-08
LK http://hdl.handle.net/10272/18942
UL http://hdl.handle.net/10272/18942
LA eng
NO Blázquez Carmona, P., Sánchez Raya, M., Mora Macías, J. ... Gómez Galán, J. A. (2020). Real-Time Wireless Platform for In Vivo Monitoring of Bone Regeneration. Sensors, 20(16), 4591. DOI: https://doi.org/10.3390/s20164591
DS Repositorio Institucional de la Universidad de Huelva
RD 1 jun 2026