RT Journal Article T1 Effects of Prehabilitation on Functional Capacity in Aged Patients Undergoing Cardiothoracic Surgeries: A Systematic Review A1 Fernández Costa, Damián A1 Gómez Salgado, Juan A1 Castillejo del Río, Andrés A1 Borrallo Riego, Álvaro A1 Guerra Martín, María Dolores AB Background: an increasing number of advanced age patients are considered for cardiothoracic surgeries. Prehabilitation optimizes the patients’ functional capacity and physiologicalreserve. However, the effectiveness of prehabilitation on physical functioning and postoperativerecovery in the scope of cardiothoracic surgery is still uncertain. Objective: to assess the effectivenessof prehabilitation on pre- and/or postoperative functional capacity and physiological reserve inaged patients that are considered for cardiothoracic surgeries. Methods: this systematic reviewwas registered in PROSPERO (CRD42021247117). The searches were conducted in PubMed, Webof Science, Scopus, and Cochrane CENTRAL until 18 April 2021. Randomized clinical trials thatcompared different prehabilitation strategies with usual care on the pre- and-postoperative resultsin aged patients undergoing cardiothoracic surgeries were included. Methodological quality wasassessed by means of the Jadad scale, and the effectiveness of the interventions according to theConsensus on Therapeutic Exercise Training. Results: nine studies with 876 participants aged from64 to 71.5 years old were included. Risk of bias was moderate due to the absence of double-blinding.The content of the interventions (multimodal prehabilitation n = 3; based on physical exercises n = 6)and the result measures presented wide variation, which hindered comparison across the studies. Ingeneral, the trials with better therapeutic quality (n = 6) reported more significant improvements inphysical functioning, cardiorespiratory capacity, and in the postoperative results in the participantsunder-going prehabilitation. Conclusions: prehabilitation seems to improve functional capacity andpostoperative recovery in aged patients undergoing cardiothoracic surgeries. However, due to the significant heterogeneity and questionable quality of the trials, both the effectiveness of prehabilitationand the optimum content are still to be determined PB MDPI SN 2227-9032 (electrónico) YR 2021 FD 2021 LK http://hdl.handle.net/10272/20303 UL http://hdl.handle.net/10272/20303 LA eng NO Fernández-Costa, D., Gómez-Salgado, J., Castillejo del Río, A., Borrallo-Riego, Á., & Guerra-Martín, M. D. (2021). Effects of Prehabilitation on Functional Capacity in Aged Patients Undergoing Cardiothoracic Surgeries: A Systematic Review. In Healthcare (Vol. 9, Issue 11, p. 1602). MDPI AG. https://doi.org/10.3390/healthcare9111602 DS Repositorio Institucional de la Universidad de Huelva RD 30 may 2026