@article{10272/18995,
year = {2020},
month = {10},
url = {http://hdl.handle.net/10272/18995},
abstract = {Biomass of the acidophilic green alga Coccomyxa onubensis may be used as a food source for animals without collateral toxic
effects, as diet supplemented the microalga has significant hypoglycemic and hypocholesterolemic effects on healthy animals.
Rats were fed for 108 days with a high-fat diet, and at the end of the experiment, they were overweight and had significantly
increased serum levels of glucose (2.0-fold), total cholesterol (1.6-fold), and low-density lipoprotein (LDL)-cholesterol (7.7-
fold). The supplement of C. onubensis powder (6.25% w/w dry weight) in the high-fat diet significantly protected the rats against
cardiovascular risks by reducing the serum levels of glucose (38.47%), total cholesterol (22.65%), and LDL-cholesterol
(26.70%). The protective effects of the microalga were comparable with that of 10 mg/kg body weight per day of atorvastatin.
The high-fat diet decreased both ω–3 eicosapentaenoic and docosahexaenoic acids in the brain tissue of rats; however,
C. onubensis powder could not restrict these changes. Simultaneously, the high-fat diet increased the levels of both palmitic
and arachidonic (ω–6) acids in the telencephalon tissue of rats; this was prevented when microalga biomass was used in the diet
of rats.},
publisher = {Springer},
title = {The acidophilic microalga Coccomyxa onubensis and atorvastatin equally improve antihyperglycemic and antihyperlipidemic protective effects on rats fed on high-fat diets},
doi = {10.1007/s10811-020-02280-4},
author = {Navarro Roldán, Francisco Juan and Toimil, Alberto and Ramírez, Sara and Montero, Yina},
}