RT Journal Article
T1 Iron and Manganese Catalysts for the Selective Functionalization of Arene C(sp(2))-H Bonds by Carbene Insertion
T1 Introducing Fe and Mn as catalysts for the selective functionalization of Csp2-H bonds of arenes by carbene insertion
A1 Conde Alcántara, Ana Isabel
A1 Sabenya, Gerard
A1 Rodríguez, Mònica
A1 Postils, Verònica
A1 Luis, Josep M.
A1 Díaz Requejo, María Mar
A1 Costas, Miquel
A1 Pérez Romero, Pedro José
AB The first examples of the direct functionalization of non-activated aryl sp(2) C-H bonds with ethyl diazoacetate (N2CHCO2Et) catalyzed by Mn- or Fe-based complexes in a completely selective manner are reported, with no formation of the frequently observed cycloheptatriene derivatives through competing Buchner reaction. The best catalysts are Fe-II or Mn-II complexes bearing the tetradentate pytacn ligand (pytacn = 1-(2-pyridylmethyl)-4,7-dimethyl-1,4,7-triazacyclononane). When using alkylbenzenes, the alkylic C(sp(3))-H bonds of the substituents remained unmodified, thus the reaction being also selective toward functionalization of sp(2) C-H bonds.
PB Wiley
SN 1433-7851
SN 1521-3773 electrónico
YR 2016
FD 2016
LK http://hdl.handle.net/10272/16239
UL http://hdl.handle.net/10272/16239
LA eng
NO Conde, A., Sabenya, G., Rodríguez, M., Postils, V., Luis, J. M., Díaz-Requejo, M. M., … Pérez, P. J. (2016). Iron and Manganese Catalysts for the Selective Functionalization of Arene C(sp2 )−H Bonds by Carbene Insertion. Angewandte Chemie International Edition, 55(22), 6530–6534. https://doi.org/10.1002/anie.201601750
NO Título de la versión post-print: Introducing Fe and Mn as catalysts for the selective functionalizationof Csp2-H bonds of arenes by carbene insertion
NO Support for this work was provided by the MINECO (CTQ2014-52769-C3-R-1, CTQ2014-62234-EXP, CTQ2015-70795-P, CTQ2014-54306-P, and CTQ2014-52525P), and the Junta de Andalucia (P10-FQM-06292). A.C. thanks Junta de Andalucia for a research contract. M.C. acknowledges an ICREA Academia Award, 2014 SGR 862 from Generalitat de Catalunya, and ERC-239910.
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026