RT Journal Article
T1 Identifying internalizing transdiagnostic profiles through motivational and cognitive control systems: Relations with symptoms, functionality, and quality of life
A1 Verdejo García, Antonio
A1 Rossi, Gina
A1 Albein Urios, Natalia
A1 Lozano Rojas, Óscar Martín
A1 Díaz Batanero, María Carmen
AB Background: The diversity of patients' symptomatology among people seeking treatment on community-based mental health services poses significant challenges to traditional models of care. Recent approaches favor identifying transdiagnostic factors that allow a better understanding of patient heterogeneity and designing more effective and quality interventions. This study examines the heterogeneity of patients with internalizing symptoms based on profiles identified with cognitive and motivational control variables. Differences between these profiles on dimensional measures of psychopathology and quality of life are examined.Methods: 263 patients were selected by non-probabilistic sampling procedures on mental health services in the province of Huelva (Spain). A latent class analysis on the standardized scale scores of The Behavioral Inhibition/Behavioral Activation System Scales and the Effortful Control Scale of the Adult Temperament Questionnaire Short-Form was conducted. Profiles were compared on the scores of the Inventory of Depression and Anxiety Symptoms-II, the WHO Disability Assessment Schedule II, and the Health Assessment Questionnaire SF-36.Results: The four latent profile solution is the one that showed the best fit indicators and substantive interpretability, with a kappa of 0.94 in the cross-validation procedure with 75% of the sample. No sex differences were found between the profiles (χ32 5.17, p = .160). Profiles #1 and #3, both characterized by an imbalance between low activation and high inhibition, had lower well-being, lower functionality, and quality of life. When comparing profile #2 (featuring the highest inhibitory control) lower scores on most internalizing scales are observed, specially claustrophobia, social anxiety, panic mania. Profile #4 (low control, high activation, and high inhibition) showed greater scores on both mania and euphoria and lower scores on emotional role.Conclusions: We identified four distinctive profiles that had overly increased behavioral inhibition (as expected in internalizing disorders) and differed in the degree of imbalance between inhibition and activation systems, and between motivational systems and top-down cognitive control. The profile characterized by high activation and reduced cognitive (inhibitory) control was the one showing greater mood-related symptoms and lower levels of quality of life. These profiles could be generated by treatment providers to guide clinical management in an evidence-based manner.
PB Elsevier
SN 0010-440X
YR 2024
FD 2024-05
LK https://hdl.handle.net/10272/24017
UL https://hdl.handle.net/10272/24017
LA eng
NO Verdejo-Garcia, A., Rossi, G., Albein-Urios, N., Lozano, O. M., & Diaz-Batanero, C. (2024). Identifying internalizing transdiagnostic profiles through motivational and cognitive control systems: Relations with symptoms, functionality, and quality of life. In Comprehensive Psychiatry (Vol. 133, p. 152498). Elsevier BV. https://doi.org/10.1016/j.comppsych.2024.152498
NO This study has been funded by the project "Reliable and clinicalrelevant change of Inventory of Depression and Anxiety Symptoms-II –IDAS-II: a longitudinal clinical utility study (RELY-IDAS-II)", grantPID2020-116187RB-I00 on Proyectos I+D+i 2020 “Retos del Conocimiento”funded by MCIU/AEI/10.13039/501100011033/ and byAyudas María Zambrano SOL-RPU-57 and SOL-RPU-65 funded bySpanish Ministry of Universities (University of Huelva) and EuropeanUnion NextGenerationEU. Funding for open access charge: Universidadde Huelva / CBUA.
DS Repositorio Institucional de la Universidad de Huelva
RD 30 may 2026