RT Journal Article
T1 Relationship between Night Shifts and Risk of Breast Cancer among Nurses: A Systematic Review
A1 Fagundo Rivera, Javier
A1 Gómez Salgado, Juan
A1 García Iglesias, Juan Jesús
A1 Ruiz Frutos, Carlos
AB Background and objectives: The incidence of breast cancer worldwide has increased in recentdecades, accounting for 1 in 3 neoplasms in women. Besides, nurses are mainly represented by thefemale collective, most of them, undertaking working conditions with intensive rotative and nightshifts due to the 24-h pace of work of this profession. The objective of this study was to assess thepossible relationship between shift work, especially night-time work, and the development of breastcancer among nurses. Materials and Methods: A systematic review of the literature was carried outthrough the consultation of the following databases: Cochrane Plus Library, PubMed, CINAHL(Cumulative Index to Nursing and Allied Health Literature), Web of Science, ScienceDirect, Scopus,and Dialnet. Records were selected between 2010 and 2020, in Spanish and English, which coveredthe association between breast cancer diagnosed among nursing professionals and rotating nightshifts. Results: A total of 12 studies were identified after critical reading. Most of the studies foundan association between breast cancer and consecutive rotating night shifts prolonged over time.Among the associated factors, the alteration of the circadian rhythm influenced the expression ofperipheral clock genes, which was the same as reproductive hormones. The risk of breast cancer innurses increased during early adulthood and after 5 or more years with 6 or more consecutive nights.Conclusions: The different studies of this review show significant associations between breast cancerand prolonged rotating night shifts. Similarly, there is a relationship between the alterations in certaincircadian rhythm markers (such as melatonin), epigenetic markers (such as telomeres), and breastcancer that would require more studies in order to corroborate these findings.
PB MDPI
SN 1648-9144
YR 2020
FD 2020-12
LK http://hdl.handle.net/10272/19530
UL http://hdl.handle.net/10272/19530
LA eng
NO Fagundo Rivera, J., Gómez Salgado, J., García Iglesias, J. J. ... Ruiz Frutos, C. (2020). Relationship between Night Shifts and Risk of Breast Cancer among Nurses: A Systematic Review. Medicina, 56(12), 680. DOI: https://doi.org/10.3390/medicina56120680
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026