RT Journal Article T1 Monitoring adherence and abstinence of cannabis use disorder patients: profile identification and relationship with long term treatment outcomes A1 Dacosta Sánchez, Daniel A1 Fernández Calderón, Fermín A1 Blanc Molina, Andrea A1 Díaz Batanero, María Carmen A1 Lozano Rojas, Óscar Martín AB Background: Patients with cannabis use disorder (CUD) show heterogeneous sociodemographic and consumptionpatterns. Although previous studies, focused on identifying subgroups of CUD patients using input variables,have yielded useful results for planning individualized treatments, no published research has analyzed theprofiles of CUD patients according to their therapeutic progress. This study therefore aims to identify subgroupsof patients using adherence and abstinence indicators and to explore whether these profiles are associated withsociodemographic characteristics, consumption variables, and long-term therapeutic outcomes.Methods: This was a retrospective observational study with a multisite sample of 2055 CUD outpatients who werebeginning treatment. The study monitored patient data at two-year follow-up. We conducted latent profilesanalysis on the appointment attendance ratio and percentage of negative cannabis tests.Results: A three profile solution emerged: i) moderate abstinence/moderate adherence (n = 997); ii) highabstinence/moderate adherence (n = 613); and iii) high abstinence/high adherence (n = 445). The study foundthe most marked differences at the beginning of treatment for education level (chi2 (8) = 121.70, p < .001),source of referral (chi2 (12) = 203.55, p < .001), and frequency of cannabis use (chi2 (10) = 232.39, p < .001).Eighty percent of patients from the “high abstinence/high adherence” group were relapse-free at two year follow-up. This percentage decreased to 24.3 % in the “moderate abstinence/moderate adherence” group.Conclusions: Research has shown adherence and abstinence indicators to be useful for identifying subgroups ofpatients with different prognoses regarding long-term success. Recognizing the sociodemographic and con-sumption variables associated with these profiles at the beginning of treatment could help to inform the design ofmore individualized interventions PB Elsevier SN 2949-8759 YR 2023 FD 2023 LK https://hdl.handle.net/10272/22554 UL https://hdl.handle.net/10272/22554 LA eng NO Dacosta-Sánchez, D., Fernández-Calderón, F., Blanc-Molina, A., Díaz-Batanero, C., & Lozano, O. (2023). Monitoring adherence and abstinence of cannabis use disorder patients: profile identification and relationship with long term treatment outcomes. Journal of Substance Use and Addiction Treatment, 148(2023), 209019. https://doi.org/10.1016/j.josat.2023.209019 NO Funding for open access charge: Universidad de Huelva / CBUA DS Repositorio Institucional de la Universidad de Huelva RD 1 jun 2026