RT Journal Article T1 Establishing the macular grading grid by means of fovea centre detection using anatomical-based and visual-based features A1 Aquino Martín, Arturo AB This paper presents a methodology for establishing the macular grading grid in digital retinal images by means of fovea centre detection. Usually, visual and anatomical feature based criteria have been used separately for fovea segmentation. However, the combination of the benefits of both techniques constitutes the core methodology presented throughout this paper. Firstly, an acceptable fovea centre estimation is obtained by using a priori-known anatomical feature with respect to the optic disc and the vascular tree. Secondly, a type of morphological processing attempts to improve the obtained fovea centre estimation when the fovea is detectable in the image; otherwise it is declared indistinguishable and the first result is retained. The methodology was tested on the MESSIDOR and DIARETDB database using a distance criterion between the obtained and the real fovea centre. Fovea centres in the brackets between Excellent-Fair (fovea centres primarily accepted as valid in the literature) made up 97.42% and 95.51% of all cases in the MESSIDOR and DIARETDB, respectively. PB Elsevier SN 0010-4825 SN 1879-0534 (electrónico) YR 2014 FD 2014 LK https://hdl.handle.net/10272/23052 UL https://hdl.handle.net/10272/23052 LA eng NO Aquino, A. (2014). Establishing the macular grading grid by means of fovea centre detection using anatomical-based and visual-based features. In Computers in Biology and Medicine (Vol. 55, pp. 61–73). Elsevier BV. https://doi.org/10.1016/j.compbiomed.2014.10.007 NO The author would like to thank the MESSIDOR and DIARETDB1 program partners for facilitating their database. DS Repositorio Institucional de la Universidad de Huelva RD 15 jun 2026