RT Journal Article
T1 Fe (III)-Mediated Antioxidant Response of the Acidotolerant Microalga Coccomyxa onubensis
A1 Robles Garrido, María
A1 Torronteras Santiago, Rafael
A1 Ostojic, Carol
A1 Oria, Cinta
A1 Cuaresma Franco, María
A1 Garbayo Nores, Inés
A1 Navarro Roldán, Francisco Juan
A1 Vílchez Lobato, Carlos
AB Coccomyxa onubensis (C. onubensis) is an acidotolerant microalga isolated from Tinto River(Huelva), which contains high levels of metal cations in solution, mainly Fe (II) and (III), and Cu (II).Fe is more bioavailable at low pH, mainly because Fe (II) and Fe (III) are far more soluble, especiallyFe (III). For this reason, this study aims to evaluate both physiological and biochemical responsesof C. onubensis when subjected to Fe (III)-induced stress. Changes in growth, photosyntheticviability and antioxidant responses to the induced oxidative stress were determined. The resultsobtained suggest that the addition of moderate Fe (III) levels to C. onubensis cultures results inimproved growth and photosynthetic viability. Increases in the intracellular levels of the enzymesuperoxide dismutase (SOD) and flavonoids, used as antioxidant response biomarkers, a pointat Fe (III)-mediated oxidative stress induction. The apparent decrease in the content of otherphenolic molecules and polyunsaturated fatty acids might be understood as a sign of antioxidantmolecules' involvement in reactive oxygen species (ROS) scavenging. In conclusion, a noticeableantioxidant capacity displayed by C. onubensis allows the use of moderate Fe (III) levels to triggerthe accumulation of valuable antioxidant molecules, allowing the production of cell extracts withpotential anti-inflammatory activity.
PB MDPI
SN 10.3390/antiox12030610
SN 2076-3921 (electrónico)
YR 2023
FD 2023
LK https://hdl.handle.net/10272/22004
UL https://hdl.handle.net/10272/22004
LA eng
NO Robles, M.; Torronteras, R.; Ostojic, C.; Oria, C.; Cuaresma, M.; Garbayo, I.; Navarro, F.; Vílchez, C. Fe (III)-Mediated Antioxidant Response of the Acidotolerant Microalga Coccomyxa onubensis. Antioxidants 2023, 12, 610. https:// doi.org/10.3390/antiox12030610
NO This work was funded by the Andalusian Research, Development and Innovation Plan(Junta de Andalucía, Spain) with FEDER funds (Project P20_00930).
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026