RT Journal Article
T1 Garlicinals A−D: Bioactive Organosulfur α,β-Unsaturated Aldehydes from Garlic (Allium sativum L.) Hydrolate
A1 Galisteo Pretel, Alberto
A1 Quílez del Moral, José F.
A1 Barrero, Alejandro F.
A1 Andrés, María F.
A1 Gonzalez Coloma, Azucena
AB Four sulfur-derived compounds, garlicinals A–D (1–4), were isolated from the garlic (Allium sativum) bulb hydrolate. The structural elucidation of 1–4 was achieved with the help of HRMS and 1D and 2D NMR. All of these compounds are characterized by an α,β-unsaturated aldehyde in their structure. Noteworthy, this structural motif is unique in garlic-derived compounds, which would convert them into a new family of garlic-derived organosulfur compounds. A synthetic path to these compounds is proposed. Garlicinals A–C showed potent fungicidal activity against plant pathogens (Aspergillus niger and Botrytis cinerea). Furthermore, 1–4 were active against the nematode Meloidogyne javanica.
PB American Chemical Society
YR 2025
FD 2025
LK https://hdl.handle.net/10272/27410
UL https://hdl.handle.net/10272/27410
LA eng
NO Galisteo, A., Quílez del Moral, J. F., Barrero, A. F., F Andrés, M., & Gonzalez-Coloma, A. (2025). Garlicinals A–D: Bioactive Organosulfur α,β-Unsaturated Aldehydes from Garlic (                     Allium sativum                     L.) Hydrolate. ACS Omega. https://doi.org/10.1021/acsomega.5c09432
NO This research has been funded by grants MINISTERIO DE CIENCIA: PID2024-156361OB-C22, CDTI R&D Contract COOPAMAN-CSIC (20190780). Funding for open access charge: Universidad de Huelva/CBUA.
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026