RT Journal Article T1 Prognostic factors affecting return to work in cancer patients: a systematic review A1 López Faneca, Lydia A1 Ruiz Frutos, Carlos A1 Gómez Salgado, Juan A1 Fagundo Rivera, Javier A1 Palomo Gómez, Rocío A1 Allande Cussó, Regina A1 Ruger Navarrete, Azahara A1 Macías Toronjo, Israel A1 García Iglesias, Juan Jesús AB Return-to-work rates among working-age cancer survivors present a complex challenge, varying by cancer type and individual characteristics. This study aimed to identify prognostic factors influencing return to work in cancer survivors. A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Searches in PubMed, Scopus, and Web of Science databases in December 2024 used keywords based on the Population, Prognostic Factors, Outcomes framework to identify relevant studies. Study quality was evaluated using Joanna Briggs Institute tools, and the protocol was registered in PROSPERO (CRD42024596102). Twenty studies were selected. Identified factors included sociodemographic: older age, educational level, marital status, and sex; clinical: aggressive treatments, comorbidities, and physical sequelae; psychological: anxiety, stress, fear of relapse, and social support; occupational: flexible work schedules and tasks versus rigid conditions. Multiple factors influence return-to-work outcomes for cancer survivors. Individualised intervention programmes addressing specific patient needs and fostering adapted work environments are essential to promote successful reintegration. PB BMJ PUBLISHING GROUP SN 1470-7926 YR 2025 FD 2025 LK https://hdl.handle.net/10272/27158 UL https://hdl.handle.net/10272/27158 LA eng NO López-Faneca, L., Ruiz-Frutos, C., Gómez-Salgado, J., Fagundo-Rivera, J., Palomo-Gómez, R., Allande-Cussó, R., Ruger-Navarrete, A., Macías-Toronjo, I., & García-Iglesias, J. J. (2025). Prognostic factors affecting return to work in cancer patients: a systematic review. Occupational and Environmental Medicine, 82(6), 305–312. https://doi.org/10.1136/oemed-2025-110212 NO This work was funded by the Instituto Andaluz de Prevención de Riesgos Laborales: Project PII/2024/0013—Guidelines for managing return to work after sick leave due to cancer. DS Repositorio Institucional de la Universidad de Huelva RD 13 jun 2026