RT Journal Article
T1 Chemically-Induced Production of Anti-Inflammatory Molecules in Microalgae
A1 Montero Lobato, Zaida
A1 Vázquez, María
A1 Navarro Domínguez, Francisco Javier
A1 Fuentes Cordero, Juan Luis
A1 Bermejo, Elisabeth
A1 Garbayo Nores, Inés
A1 Vílchez Lobato, Carlos
A1 Cuaresma Franco, María
AB Microalgae have been widely recognized as a valuable source of natural, bioactive moleculesthat can benefit human health. Some molecules of commercial value synthesized by the microalgalmetabolism have been proven to display anti-inflammatory activity, including the carotenoids luteinand astaxanthin, the fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid),and sulphated polysaccharides. These molecules can accumulate to a certain extent in a diversity ofmicroalgae species. A production process could become commercially feasible if the productivity ishigh and the overall production process costs are minimized. The productivity of anti-inflammatorymolecules depends on each algal species and the cultivation conditions, the latter being mostly relatedto nutrient starvation and/or extremes of temperature and/or light intensity. Furthermore, novelbioprocess tools have been reported which might improve the biosynthesis yields and productivityof those target molecules and reduce production costs simultaneously. Such novel tools include theuse of chemical triggers or enhancers to improve algal growth and/or accumulation of bioactivemolecules, the algal growth in foam and the surfactant-mediated extraction of valuable compounds.Taken together, the recent findings suggest that the combined use of novel bioprocess strategiescould improve the technical efficiency and commercial feasibility of valuable microalgal bioproductsproduction, particularly anti-inflammatory compounds, in large scale processes.
PB MDPI
SN 1660-3397
YR 2018
FD 2018-11
LK http://hdl.handle.net/10272/16116
UL http://hdl.handle.net/10272/16116
LA eng
NO Montero-Lobato, Z., Vázquez, M., Navarro, F., Fuentes, J., Bermejo, E., Garbayo, I., … Cuaresma, M. (2018). Chemically-Induced Production of Anti-Inflammatory Molecules in Microalgae. Marine Drugs, 16(12), 478. https://doi.org/10.3390/md16120478
NO Z.M.-L. is beneficial of a predoctoral grant from "Plan Propio de Investigacion" from the University of Huelva (Spain). Part of the scientific information reviewed in this paper (Section 3) was produced within the MIRACLES project which is supported by the European Commission Seventh Framework Programme under Grant Agreement No. 613588.
DS Repositorio Institucional de la Universidad de Huelva
RD 1 jun 2026