RT Journal Article T1 Multiscale Characterisation of Cortical Bone Tissue A1 Sanz Herrera, José A. A1 Mora Macías, Juan A1 Reina Romo, Esther A1 Domínguez, Jaime A1 Doblaré, Manuel AB Multiscale analysis has become an attractive technique to predict the behaviour ofmaterials whose microstructure strongly changes spatially or among samples, with that microstructurecontrolling the local constitutive behaviour. This is the case, for example, of most biologicaltissues—such as bone. Multiscale approaches not only allow, not only to better characterise the localbehaviour, but also to predict the field-variable distributions (e.g., strains, stresses) at both scales(macro and micro) simultaneously. However, multiscale analysis usually lacks su cient experimentalfeedback to demonstrate its validity. In this paper an experimental and numerical micromechanicsanalysis is developed with application to cortical bone. Displacement and strain fields are obtainedacross the microstructure by means of digital image correlation (DIC). The other mechanical variablesare computed following the micromechanics theory. Special emphasis is given to the di erencesfound in the di erent field variables between the micro- and macro-structures, which points out theneed for this multiscale approach in cortical bone tissue. The obtained results are used to establishthe basis of a multiscale methodology with application to the analysis of bone tissue mechanics atdi erent spatial scales. PB MDPI SN 2076-3417 YR 2019 FD 2019-12 LK http://hdl.handle.net/10272/17635 UL http://hdl.handle.net/10272/17635 LA eng NO Sanz Herrera, J. A., Mora Macías, J., Reina Romo, E., Domínguez, J., Doblaré, M. (2019). Multiscale Characterisation of Cortical Bone Tissue. Applied Sciences, 9(23), 5228. DOI: https://doi.org/10.3390/app9235228 NO The authors gratefully acknowledge the Ministry of Economy and Competitiveness [Ministerio de Economia y Competitividad] of the Government of Spain (DPI2014-58233-P, DPI2017-82501-P, PGC2018-097257-B-C31) for research funding. DS Repositorio Institucional de la Universidad de Huelva RD 1 jun 2026