RT Journal Article
T1 Profiles of Patients with Cocaine and Alcohol use Disorder Based on Cognitive Domains and Their Relationship with Relapse
A1 Dacosta Sánchez, Daniel
A1 González Ponce, Bella M.
A1 Fernández Calderón, Fermín
A1 Lozano Rojas, Óscar Martín
AB Background: Relapse in drug use constitutes a research topic on addiction that isrelevant for understanding both the addictive process and its clinical implications. Theobjective of this study was to explore if it is possible to identify patient profilesaccording to their performance on cognitive tasks whilst examining the relationshipbetween such profiles and relapse. Methods: The sample consisted of 222 patients withdependence on cocaine and / or alcohol, of which 86% were men. Cognitive domainsrelated to salience, decision- making, and emotional processing were measured.Results: Latent class analysis revealed three patient profiles that differ in terms ofperformance on cognitive tasks. Two of these profiles are clearly differentiated in termsof their execution of the impulsive decision-making task. The third patient profile,unlike the latter two, is composed of patients with severe alterations in the threedomains evaluated. Analysis revealed that patients in Profile 3 are those with thehighest rates of relapse in cocaine (Profile 1 = 40.3%; Profile 2 = 35.6%; Profile 3 =69.2%; Chi2 = 9.169; p <.05) and cocaine and alcohol use (Profile 1 = 55.1%; Profile 2= 54.1%; Profile 3 = 80%; Chi2 = 6.698; p <.05). Conclusions: The results support thepostulates of the I-RISA model. From a clinical perspective, these findings highlight theneed for a comprehensive evaluation of the cognitive domains involved in addiction.
PB Elsevier
SN 0376-8716
YR 2021
FD 2021-01
LK http://hdl.handle.net/10272/19722
UL http://hdl.handle.net/10272/19722
LA eng
NO Dacosta Sánchez, D., González Ponce, B. M., Fernández Calderón, F. ... Lozano Rojas, O. M. (2021). Profiles of patients with cocaine and alcohol use disorder based on cognitive domains and their relationship with relapse. Drug and Alcohol Dependence, 218, 108349. DOI: https://doi.org/10.1016/j.drugalcdep.2020.108349
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026