RT Journal Article
T1 Relative Handgrip Strength Diminishes the Negative Effects of Excess Adiposity on Dependence in Older Adults: A Moderation Analysis
A1 Pérez Sousa, Miguel Ángel
A1 Ramírez Vélez, Robinson
A1 García Hermoso, Antonio
A1 Zambom Ferraresi, Fabrício
A1 Martínez Velilla, Nicolás
A1 Sáez de Asteasu, Mikel L.
A1 Cano Gutiérrez, Carlos A.
A1 Rincón Pabón, David
A1 Izquierdo, Mikel
AB The adverse e ects of fat mass on functional dependence might be attenuated or worsened,depending on the level of muscular strength. The aim of this study was to determine (i) the detrimentaleffect of excess adiposity on dependence in activities of daily living (ADL), and (ii) whether relativehandgrip strength (HGS) moderates the adverse effect of excess adiposity on dependence, and toprovide the threshold of relative HGS from which the adverse e ect could be improved or worsened.A total of 4169 participants (69.3 +- 7.0 years old) from 244 municipalities were selected followinga multistage area probability sampling design. Measurements included anthropometric/adipositymarkers (weight, height, body mass index, waist circumference, and waist-to-height ratio (WHtR)),HGS, sarcopenia “proxy” (calf circumference), and ADL (Barthel Index scale). Moderation analyseswere performed to identify associations between the independent variable (WHtR) and outcomes(dependence), as well as to determine whether relative HGS moderates the relationship betweenexcess adiposity and dependence. The present study demonstrated that (i) the adverse e ect of havinga higher WHtR level on dependence in ADL was moderated by relative HGS, and (ii) two moderationthresholds of relative HGS were estimated: 0.35, below which the adverse effect of WHtR levels ondependency is aggravated, and 0.62, above which the adverse effect of fat on dependency could beimproved. Because muscular strength represents a critically important and modifiable predictor ofADL, and the increase in adiposity is inherent in aging, our results underscore the importance of anoptimal level of relative HGS in the older adult population.
PB MDPI
SN 2077-0383
YR 2020
FD 2020-04
LK http://hdl.handle.net/10272/17940
UL http://hdl.handle.net/10272/17940
LA eng
NO Ramírez Vélez, R., Pérez Sousa, M. Á., García Hermoso, A. ... Zambom Ferraresi, F. (2020). Relative Handgrip Strength Diminishes the Negative Effects of Excess Adiposity on Dependence in Older Adults: A Moderation Analysis. Journal of Clinical Medicine, 9(4), 1152. DOI: https://doi.org/10.3390/jcm9041152
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026