RT Journal Article
T1 Differential Contribution of Drug Classes to Impulsive Behaviors in Patients Diagnosed with Substance Use Disorder
A1 Díaz López, Alba
A1 Lozano Rojas, Óscar Martín
A1 Moraleda Barreno, Enrique
A1 Velo Ramírez, María Sheila
AB Purpose of review: This paper synthesizes recent evidence on the differential contribution of drug classes to impulsive behaviors in patients with substance use disorder. It focuses on delineating which domains of impulsivity vary by substance class, which impulsivity dimensions predict treatment outcomes, and the principal neurobiological findings.Recent findings: Recent studies report elevated impulsivity across most substance use disorders with substance-specific patterns. Stimulants, particularly methamphetamine, produce the most pervasive deficits in inhibitory control, planning, and decision-making. Alcohol and opioids are associated with broad decision-making impairments and elevated trait impulsivity that often persist during substitution treatments. By contrast, cannabis shows the weakest and most inconsistent effects.Impulsive decision-making consistently predicts relapse. Neuroimaging implicates frontostriatal circuits, the insula, and the cingulate cortex, with substance-specific differences in regional volume, receptor availability, and network connectivity. Genetic evidence is limited and heterogeneous.Summary: Impulsivity is a transdiagnostic marker with substance-specific profiles that influence both relapse risk and treatment response. Longitudinal, comparative, and network-focused studies employing consensus measures are needed to clarify causality and inform personalized interventions.
PB Springer
SN 2196-2952 (electrónico)
YR 2026
FD 2026
LK https://hdl.handle.net/10272/28294
UL https://hdl.handle.net/10272/28294
LA eng
NO Díaz-López, A., Lozano, Ó. M., Moraleda-Barreno, E., & Velo, S. (2026). Differential Contribution of Drug Classes to Impulsive Behaviors in Patients Diagnosed with Substance Use Disorder. Current Addiction Reports, 13(1). https://doi.org/10.1007/s40429-026-00739-x
NO Funding for open access publishing: Universidad de Huelva/ CBUA. This research was supported by the project Real-time neuropsychological assessment of implicit cognition in predicting relapse in patients with substance use disorder (PID2020-119829RB-I00), funded by the Ministry of Economy, Industry and Competitiveness, Government of Spain.
DS Repositorio Institucional de la Universidad de Huelva
RD 13 jul 2026