RT Journal Article T1 First Insight into the Natural Attenuation of Emerging Contaminants Using a Metagenomics Approach from Drinking Water Sources in the Free State A1 Mqambalala, Avela A1 Maleke, Maleke A1 Deysel, Lore-Mari A1 Osman, Jorge R. A1 Gómez Arias, Alba A1 Valverde, Ángel A1 Castillo Hernández, Julio Cesar AB Emerging contaminants have gained interest over the years due to their adverse effects on the aquatic environment. Therefore, it is essential to improve the current strategies for their removal. Biodegradation has emerged as an efficient strategy driven by microorganisms through metabolism and co-metabolism pathways. Enzymes encoded by specific genes facilitate these processes. This study aimed to identify and quantify the genes involved in these pathways. The research identified bacterial species belonging to the genera Pseudomonas, Nitrosomonas, Nitrosospira, and Methylotenera, which are associated with the degradation of emerging contaminants. Additionally, it successfully identified genes linked to metabolism and co-metabolism processes within the indigenous bacteria (MAGs). The findings suggest that the native bacteria in the samples may have the natural potential to mitigate emerging contaminants in aquatic environments through the combined actions of metabolism and co-metabolism. PB MDPI SN 2076-2607 (electrónico) YR 2025 FD 2025 LK https://hdl.handle.net/10272/27370 UL https://hdl.handle.net/10272/27370 LA eng NO Mqambalala, A., Maleke, M., Deysel, L.-M., Osman, J. R., Gómez-Arias, A., Valverde, A., & Hernández, J. C. (2025). First Insight into the Natural Attenuation of Emerging Contaminants Using a Metagenomics Approach from Drinking Water Sources in the Free State. Microorganisms, 13(10), 2349. https://doi.org/10.3390/microorganisms13102349 NO This work was supported by National Research Foundation (NRF) (PMDS230718136664) and the Technology Innovation Agency (TIA) (SABDI 16/1070), Beatriz Galindo Senior Modality Program grant to the University of Huelva by the Ministry of Science, innovation and Universities of the Spanish Government (B623-00091). DS Repositorio Institucional de la Universidad de Huelva RD 30 may 2026