RT Journal Article
T1 Influence of Nutritional Parameters on the Evolution, Severity and Prognosis of Critically Ill Patients with COVID-19
A1 Gamarra Morales, Yenifer
A1 Molina López, Jorge
A1 Machado Casas, Juan Francisco
A1 Herrera Quintana, Lourdes
A1 Vázquez-Lorente, Héctor
A1 Castaño Pérez, José
A1 Pérez Villares, José Miguel
A1 Planells, Elena
AB This study evaluated the clinical and nutritional status, the evolution over three days, and the relationship between nutritional, inflammatory, and clinical parameters of critically ill patients with COVID-19. A longitudinal study was conducted in the Intensive Care Unit of the Virgen de las Nieves University Hospital in Granada (Spain). The study population comprised patients with a positive polymerase chain reaction test for COVID-19 presenting critical clinical involvement. Clinical outcomes were collected, and inflammatory and nutritional parameters (albumin, prealbumin, transferrin, transferrin saturation index, cholesterol, triglycerides and Controlling Nutritional Status (CONUT) score) were determined. A total of 202 critical patients with COVID-19 were selected, presenting highly altered clinical-nutritional parameters. The evolution experienced by the patients on the third day of admission was a decrease in albumin (p < 0.001) and an increase in prealbumin (p < 0.001), transferrin (p < 0.002), transferrin saturation index (p < 0.018), and cholesterol (p < 0.001). Low levels of albumin, prealbumin (on the third day) and high CONUT score (on the third day) showed an association with higher mortality. Nutritional variables were inversely correlated with clinical and inflammatory parameters. Critically ill patients with COVID-19 have poor nutritional status related to a poor prognosis of disease severity and mortality.
PB MDPI
SN 2072-6643 (electrónico)
YR 2022
FD 2022-12
LK https://hdl.handle.net/10272/22090
UL https://hdl.handle.net/10272/22090
LA eng
NO Gamarra-Morales, Y., Molina-López, J., Machado-Casas, J. F., Herrera-Quintana, L., Vázquez-Lorente, H., Castaño-Pérez, J., Perez-Villares, J. M., & Planells, E. (2022). Influence of Nutritional Parameters on the Evolution, Severity and Prognosis of Critically Ill Patients with COVID-19. In Nutrients (Vol. 14, Issue 24, p. 5363). MDPI AG. https://doi.org/10.3390/nu14245363
NO This research was funded by Project FIS PI10/1993 from the Spanish Carlos III Health Institute and the European Regional Development Fund (ERDF) Andalucía [REF. A-CTS-708-UGR20]. L.H.-Q. [REF. FPU18/03702] and H.V.-L. [REF. FPU18/03655] were awarded an FPU fellowship from the Spanish Ministry of Education.
DS Repositorio Institucional de la Universidad de Huelva
RD 30 may 2026