RT Journal Article
T1 Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors
A1 Marcos Delgado, Alba
A1 Alguacil Ojeda, Juan
A1 Molina de la Torre, Antonio José
AB The aim of our study is to evaluate the relationship between sociodemographic and clinical characteristics of individuals with Colorectal Cancer (CRC), tumour-intrinsic characteristics and treatment received with health-related quality of life (HRQoL). Methods: Cross-sectional analysis of data from 805 survivors from the MCC study was conducted. HRQoL was assessed through a general and specific questionnaire, SF-12 and FCSI (Colorectal Symptom Index). Statistical analyses were performed with linear regression with adjustment for sociodemographic variables, stage at diagnosis and histological grade. Results: Participants had survived a median of 7.9 years from diagnosis (IQR 7.1–8.5 years). Age at diagnosis, sex and area showed a clear association with HRQoL in both physical and mental dimensions of the SF-12 questionnaire. A direct association between CRC recurrence was also found in the PCS-12 and MCS-12 dimensions and radical surgery in the PCS-12. Regarding the scores in FCSI questionnaire, statistically significant differences were observed by sex, age and area, with older women being the most impaired (p < 0.001). Conclusions: Age, sex and area was associated with lower scores of HRQoL among CRC survivors. Knowing the determinants related to HRQoL would allow us to lay the groundwork to develop strategies that help reduce morbidity and mortality, relapses and increase HRQoL.
PB MDPI
SN 2227-9032 (electrónico)
YR 2024
FD 2024-09
LK https://hdl.handle.net/10272/24286
UL https://hdl.handle.net/10272/24286
LA eng
NO Marcos-Delgado, A., Martín-Sánchez, V., Molina-Barceló, A., Alonso-Molero, J., Pérez-Gómez, B., Pollán, M., Aragonés, N., Ederra-Sanza, M., Fernández-Tardón, G., Binefa, G., Moreno, V., Barrios-Rodríguez, R., Amiano, P., Huerta, J. M., Teso, E. P., Alguacil, J., Castaño-Vinyals, G., Kogevinas, M., & Molina de la Torre, A. J. (2024). Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors. In Healthcare (Vol. 12, Issue 19, p. 1917). MDPI AG. https://doi.org/10.3390/healthcare12191917
NO This study was partially funded by the “Acción Transversal del Cancer”, approved on the Spanish Ministry Council on the 11 October 2007, by the Instituto de Salud Carlos III-FEDER (PI08/1770, PI08/0533, PS09/01286-León), by the Junta de Castilla y León (LE22A10-2), by Junta de Andalucía PI-0571(2010) and by the Instituto de Salud Carlos III (PI15/01032, PS09/2078, PI12/00265).
DS Repositorio Institucional de la Universidad de Huelva
RD 1 jun 2026