@article{10272/23239,
year = {2019},
url = {https://hdl.handle.net/10272/23239},
abstract = {Plays many key roles in health especially in connection
with cancer and neurodegenerative diseases, among others. However, it needs
to be appreciated that the essentiality or toxicity action of selenium depends on
both, a narrow range of concentration and the chemical specie involved. In this
context, human selenoproteins are essential biomolecules against these
disorders, mainly due to its antioxidant action. To this end, analytical
methodologies may allow identifying and quantifying individual selenospecies in
human biofluids and tissues.
Areas covered: This review explores the role of selenoproteins in medicine, with
special emphasis in cancer and neurodegenerative diseases, considering the
possible link with gut microbiota, and analytical techniques and procedures
recently developed for the absolute quantification of selenoproteins and
selenometabolites in human biofluids and tissues},
organization = {Projects CTM2015-67902-C2-1-P and PG2018- 096608-B-C21 from the Spanish Ministry of Economy and Competitiveness (MINECO),and by projects P12-FQM-0442 from the Regional Ministry of Economy, Innovation,
Science and Employment (Andalusian Government, Spain). Finally, authors are
grateful to FEDER (European Community) for financial support, Grant UNHU13-1E-
1611.},
publisher = {Taylor & Francis},
title = {Insights into cancer and neurodegenerative diseases through selenoproteins and the connection with gut microbiota – current analytical methodologies},
doi = {0.1080/14789450.2019.1664292},
author = {Arias Borrego, Ana and Callejón Leblic, María Belén and Calatayud, Marta and Gómez Ariza, José Luis and Collado, Maria Carmen and García Barrera, Tamara},
}