RT Journal Article
T1 Mechanochemical-assisted Natural Deep Eutectic Solvent as a platform for an olive leaves biorefinery: Extraction of bioactive compounds and methane production
A1 Cubero Cardoso, Juan
A1 Hernández Escaño, Manuel
A1 Trujillo Reyes, Ángeles
A1 González Fermoso, Fernando
A1 Fernández Recamales, María Ángeles
A1 Fernández Bolaños, Juan
A1 Rodríguez Gutiérrez, Guillermo
A1 Urbano Baena, Juan
AB This study introduces an innovative biorefinery process aimed at maximizing the utilization of olive leaves. The proposed approach seeks to extract valuable phenolic compounds, lignocellulosic material, and biomethane from olive leaves. To achieve this, a combined technique involving mechanochemical extraction and sustainable solvents, specifically natural deep eutectic solvents (NADES), was employed. Unlike conventional methods, NADES were simultaneously formed and utilized for extraction within a ball mill. The optimal conditions for maximum extraction of high-value compounds were 0.5 g of OL using 10 mL of ChCl:Gl (3:1) and 1.1 h in a ball mill. The recovered yields were 14.5 ± 2.9 g/kg OL of lignocellulosic fraction and 1.3 ± 0.3 g gallic acid eq./kg OL of phenolic compounds. OL waste generated after the optimized extraction process was evaluated for methane production, obtaining 142 ± 53 mL CH4/g VS OL waste compared to 126 ± 30 mL CH4/g VS untreated OL. Therefore, NADES represent promising solvents for the biorefinery process and reduce dependence on organic solvents.
PB Elsevier
SN 2352-5541 (electrónico)
YR 2025
FD 2025
LK https://hdl.handle.net/10272/27135
UL https://hdl.handle.net/10272/27135
LA eng
NO Cubero-Cardoso, J., Hernández-Escaño, M., Trujillo-Reyes, Á., Fermoso, F. G., Fernández-Recamales, M. Á., Fernández-Bolaños, J., Rodríguez-Gutiérrez, G., & Urbano, J. (2025). Mechanochemical-assisted Natural Deep Eutectic Solvent as a platform for an olive leaves biorefinery: Extraction of bioactive compounds and methane production. Sustainable Chemistry and Pharmacy, 43, 101879. https://doi.org/10.1016/j.scp.2024.101879
NO This work has received funding from Junta de Andalucía, within the framework of the “Programa Operativo FEDER 2014–2020” (UHU-202063).
DS Repositorio Institucional de la Universidad de Huelva
RD 1 jun 2026