@article{10272/19698,
year = {2020},
month = {3},
url = {http://hdl.handle.net/10272/19698},
abstract = {The catalytic functionalization of pyrroles by incorporation of a nitrene group is reported. The Cα‐H bond of 1H‐pyrrole is amidated upon the formal insertion of the NTs (Ts=p‐toluenesulfonyl) group catalyzed by TpBr3Cu(NCMe) (TpBr3=hydrotris(3,4,5‐tribromo‐pyrazolyl)borate). N‐substituted pyrroles also verify the same transformation. The mechanism proposal is similar to that previously described for benzene amidation with the same catalyst and PhI=NTs, which takes place through aziridine formation, ring opening and 1,2‐hydrogen shift. A cascade reaction involving the coupling of 2,5‐dimethylfuran, 1,2,3‐trimethyl‐pyrrole and a nitrene NTs group is also described, leading to a 1,2‐dihydropyridine‐imine compound.},
organization = {Support for this work was provided by the MINECO (CTQ2017‐82893‐C2‐1‐R and PO FEDER 2014‐2020, UHU‐1254043). AMR and MRR thanks MEC for a FPU fellowships.},
publisher = {Wiley-VCH Verlag},
title = {Pyrrole Functionalization by Copper‐Catalyzed Nitrene Transfer Reactions},
doi = {10.1002/ijch.201900181},
author = {Moreno Rodríguez, Anabel and Ramírez Rodríguez, Manuel and Díaz Requejo, María Mar and Pérez Romero, Pedro José},
}