RT Journal Article
T1 Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch
A1 Basílio, Nuno
A1 Pischel, Uwe
AB The reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.
PB Wiley
SN 0947-6539
SN 1521-3765 (electrónico)
YR 2016
FD 2016
LK http://hdl.handle.net/10272/14653
UL http://hdl.handle.net/10272/14653
LA eng
NO Basílio, N., Pischel, U.: "Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch". Chemistry - A European Journal. Vol. 22, págs. 15208–15211, (2016). DOI: 10.1002/chem.201603331
NO This work was supported by the Spanish MINECO (grants CTQ2011-28390 and CTQ2014-54729-C2-1-P for U.P.), the Junta de Andalucia (grant P12-FQM-2140 for U.P.), the ERDF, the COST action CM1005 "Supramolecular Chemistry in Water", and the Associated Laboratory for Sustainable Chemistry-Clean Processes and Technologies-LAQV. The latter is financed by national funds from FCT/MEC (UID/QUI/50006/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265). The NMR equipment is part of The National NMR Facility, supported by the Portuguese FCT (RECI/BBB-BQB/0230/2012). N.B. gratefully acknowledges a post-doctoral grant from FCT/MEC (SFRH/BPD/84805/2012). N.B. also wishes to sincerely acknowledge Prof. Fernando Pina for his mentorship and generous support.
DS Repositorio Institucional de la Universidad de Huelva
RD 14 jul 2026