@article{10272/16193,
year = {2017},
url = {http://hdl.handle.net/10272/16193},
abstract = {A series of alkanes CnH2n+2 have been functionalized in water as the reaction medium, using a silver-based
catalyst, upon insertion of carbene (CHCO2Et from N2CHCO2Et) groups into their carbon-hydrogen bonds of hexane,
cyclohexane or 2-methylbutane, among others. The regioselectivity toward the distinct reaction sites is identical to that
found in neat alkane, the water-based system allowing the use of a much shorter excess of the hydrocarbon. This is the
first example of the intermolecular functionalization of alkanes with this strategy in water. The functionalized alkanes
partially undergoes a incorporation of a second carbene unit to provide a-(acyloxy)acetates, in an unprecedented tandem
reaction of this nature.},
organization = {Support for this work was provided by the MINECO (Nos. CTQ2014-52769-C03-01 and CTQ2014-62234-EXP). MA, RG., and S.G.R. thank MINECO for FPI fellowships. M.RR thanks MEC for a FPU fellowship.},
publisher = {ACS Catalysis},
title = {Water as reaction medium for intermolecular C-H alkane functionalization in micellar catalysis},
doi = {10.1021/acscatal.6b03669},
author = {Ávarez, María and Gava, Riccardo and Ramírez Rodríguez, Manuel and Rull, Silvia G. and Pérez Romero, Pedro José},
}