RT Journal Article
T1 Restrictive spirometry pattern is associated with low physical activity levels. A population based international study
A1 Carsin, Anne-Elie
A1 Sánchez Ramos, José Luis
A1 García Aymerich, Judith
AB Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortalityprognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and withnormal spirometry.Methods: Restrictive spirometry pattern was defined as a having post-bronchodilator FEV1/FVC≥Lower Limitof Normal and a FVC<80% predicted in two population-based studies (ECRHS-III and SAPALDIA3). Physicalactivity was measured using the International Physical Activity Questionnaire. The odds of having low physicalactivity (< 1st study-specific tertile) was evaluated using adjusted logistic regression models.Results: Subjects with a restrictive spirometry pattern (n=280/4721 in ECRHS, n=143/3570 in SAPALDIA)reported lower levels of physical activity than those with normal spirometry (median of 1770 vs 2253 MET·min/week in ECRHS, and 3519 vs 3945 MET·min/week in SAPALDIA). Subjects with a restrictive spirometry patternwere more likely to report low physical activity (meta-analysis odds ratio: 1.41 [95%CI 1.07–1.86]) than thosewith a normal spirometry. Obesity, respiratory symptoms, co-morbidities and previous physical activity levelsdid not fully explain this finding.Conclusion: Adults with a restrictive spirometry pattern were more likely to report low levels of physical activitythan those with normal spirometry. These results highlight the need to identify and act on this understudied butprevalent condition.
PB Elsevier
SN 0954-6111
SN 1532-3064 (electrónico)
YR 2019
FD 2019
LK https://hdl.handle.net/10272/25363
UL https://hdl.handle.net/10272/25363
LA eng
NO Carsin, A.-E., Fuertes, E., Schaffner, E., Jarvis, D., Antó, J. M., Heinrich, J., Bellisario, V., Svanes, C., Keidel, D., Imboden, M., Weyler, J., Nowak, D., Martinez-Moratalla, J., Gullón, J.-A., Sanchez Ramos, J. L., Caviezel, S., Beckmeyer-Borowko, A., Raherison, C., Pin, I., … Garcia-Aymerich, J. (2019). Restrictive spirometry pattern is associated with low physical activity levels. A population based international study. In Respiratory Medicine (Vol. 146, pp. 116–123). Elsevier BV. https://doi.org/10.1016/j.rmed.2018.11.017
NO The present analyses are part of the Ageing Lungs in EuropeanCohorts (ALEC) Study (www.alecstudy.org), which has receivedfunding from the European Union's Horizon 2020 research and innovationprogramme under grant agreement No. 633212. The localinvestigators and funding agencies for the European CommunityRespiratory Health Survey (ECRHS II and ECRHS III) are reported in theSupplementary Material. SAPALDIA is funded by the National ScienceFoundation Grant Nr. 33CS30-177506. Elaine Fuertes was funded fromthe European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Individual Fellowship scheme (H2020-MSCA-IF-2015; proposal number 704268). ISGlobal isa member of CERCA Programme/Generalitat de Catalunya.
DS Repositorio Institucional de la Universidad de Huelva
RD 14 jul 2026