RT Journal Article
T1 Introducing 1,3-Enyne Functionalization  by Nitrene Transfer Reaction
A1 Moreno Rodríguez, Anabel
A1 Sciortino, Giuseppe
A1 Muñoz Gutiérrez, Lidia
A1 Molina González, Francisco
A1 Maseras, Feliu
A1 Díaz Requejo, María Mar
A1 Pérez Romero, Pedro José
AB In the context of carbon-nitrogen bond formation, metal-catalyzed nitrene transfer reactions constitute a powerful transformation. Albeit many saturated and unsaturated substrates can be modified with this strategy, the incorporation of nitrene to enynes yet remains undescribed. Herein we report the first example of this transformation, leading to the formation of propargyl aziridines or to unsaturated sulfinamides, corresponding to the attack of a copper-nitrene intermediate onto the ene or yne sites. DFT studies have provided an explanation to this diverse reactivity, which is sustained on the interactions of the enyne substituent with the pyrazolyl rings of the trispyrazolylborate ancillary ligand of the catalyst.
PB Cell Press
SN 2667-1093 (electrónico)
YR 2024
FD 2024-01
LK https://hdl.handle.net/10272/23373
UL https://hdl.handle.net/10272/23373
LA eng
NO Rodríguez, A. M., Sciortino, G., Muñoz-Gutierrez, L., Molina, F., Maseras, F., Díaz-Requejo, M. M., & Pérez, P. J. (2024). Introducing 1,3-enyne functionalization by nitrene transfer reaction. In Chem Catalysis (Vol. 4, Issue 1, p. 100865). Elsevier BV. https://doi.org/10.1016/j.checat.2023.100865
NO We thank the Ministerio de Ciencia e Innovación for grants PID2020-113797RB-C21, PID2020-112825RB-I00, CES2019-000925-S,and RED2022-134074-T. We also thank Junta de Andalucía (P20-00348), Universidad de Huelva (P.O.Feder UHU-202016), and the CERCA Programme/Generalitat de Catalunya. A.M.R. thanks Ministerio de Universidades for an FPU fellowship. G.S. thanks MICINN Juan de la Cierva program, FJC2019-039135-I.
DS Repositorio Institucional de la Universidad de Huelva
RD 15 jul 2026