RT Journal Article T1 Harm Reduction strategies and drug-related negative consequences in the dance music scene: the moderating role of polysubstance use A1 Valle Vera, Belén del A1 Carmona Márquez, José A1 Vidal Giné, Claudio A1 Fernández Calderón, Fermín AB Introduction: Although simultaneous polysubstance use (SPU) is associated with greater harmsthan concurrent polysubstance use (CPU), no previous research has examined the effectiveness ofharm reduction strategies in reducing drug-related harms in people who use drugs simultaneouslyand whether these strategies have a differential impact on drug-related negative consequencesaccording to SPU patterns. Objectives: to examine the relationship between SPU patterns, harmreduction strategies and drug-related consequences experienced among people who attend dancemusic settings, and to examine the moderating role of SPU patterns in the relationship betweenharm reduction strategies and drug-related negative consequences Methods: a web-based surveywas used to gather data from 649 substance-using attendees at dance music settings (meanage=26.2, 68% male). The survey collected data on: settings of last party attended, drug use,harm reduction strategies used and drug-related negative consequences experienced during lastparty attended. Results: Latent class analysis identified two SPU profiles: Moderate SPU andSevere SPU. Participants in the severe SPU class experienced more drug-related negativeconsequences at their last party in comparison with those in the moderate SPU class. Regardlessof SPU pattern, avoiding binge drinking was related to fewer drug-related negative consequences,whilst avoiding mixing stimulants was related to fewer drug-related negative consequences onlyamong those participants in the severe simultaneous polysubstance use class. Conclusions: Thesefindings could help to inform the design of messages and tailored interventions aimed atminimizing drug-related negative consequences among people who use multiple substances inthe dance music scene. PB Taylor and Francis SN 1082-6084 YR 2021 FD 2021-03 LK http://hdl.handle.net/10272/19852 UL http://hdl.handle.net/10272/19852 LA eng NO Valle Vera, B. del ., Carmona Márquez, J., Vidal Giné, C., & Fernández Calderón, F. (2021). Harm Reduction Strategies and Drug-Related Negative Consequences in the Dance Music Scene: The Moderating Role of Polysubstance Use. Substance Use & Misuse, 56(6), 777–781. DOI: https://doi.org/10.1080/10826084.2021.1892144 DS Repositorio Institucional de la Universidad de Huelva RD 30 may 2026