RT Journal Article
T1 Umbilical Cord Milking in Infants Born at <37Weeks of Gestation: A Systematic Review and Meta-Analysis
A1 Ortiz Esquinas, Inmaculada
A1 Gómez Salgado, Juan
A1 Rodríguez Almagro, Julián Javier
A1 Arias Arias, Ángel
A1 Ballesta Castillejos, Ana
A1 Hernández Martínez, Antonio
AB Umbilical cord milking (UCM) could be an alternative in cases where delayed umbilical cordclamping cannot be performed, therefore our objective was to evaluate the effects ofUCMin newborns<37 weeks’ gestation. In this systematic review and meta-analysis, we searched MEDLINE, EMBASE,CINAHL, the Cochrane Database of Clinical Trials, the clinicaltrails.gov database for randomizedUCMclinical trials with no language restrictions, which we then compared with other strategies. The sampleincluded 2083 preterm infants. The results of our meta-analysis suggest thatUCMin premature infantscan reduce the risk of transfusion (relative risk (RR)= 0.78 [95% confidence interval (CI),0.67–0.90])and increase hemoglobin(pooled weighted mean difference (PWMD)= 0.89 g/L[95%CI 0.55–1.22]) andmean blood pressure (PWMD=1.92 mmHg [95% CI 0.55–3.25]). Conversely, UCM seems to increasethe risk of respiratory distress syndrome (RR = 1.54 [95% CI 1.03–2.29]), compared to the controlgroups. In infants born at <33 weeks,UCMwas associated with a reduced risk of transfusion (RR= 0.81[95%CI 0.66–0.99]), as well as higher quantities of hemoglobin (PWMD= 0.91 g/L[95%CI 0.50–1.32]).UCM reduces the risk of transfusion in preterm infants, and increases initial hemoglobin, hematocrit,and mean blood pressure levels with respect to controls.
PB MDPI
SN 2077-0383
YR 2020
FD 2020-04
LK http://hdl.handle.net/10272/18314
UL http://hdl.handle.net/10272/18314
LA eng
NO Ortiz Esquinas, I., Gómez Salgado, J., Rodríguez Almagro, J., Arias Arias, Á., Ballesta Castillejos, A., & Hernández Martínez, A. (2020). Umbilical Cord Milking in Infants Born at <37 Weeks of Gestation: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 9(4), 1071. DOI: https://doi.org/10.3390/jcm9041071
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026