@article{10272/22139,
year = {2023},
month = {3},
url = {https://hdl.handle.net/10272/22139},
abstract = {Chitosan (CTS) is a polysaccharide with a wide variety of applications in the biomedical field, owing to its outstanding disinfectant properties, biocompatibility and biodegradability, but with limited mechanical properties. The proposed strategy to improve CTS-based hydrogel properties in this study is the formation of a semi-interpenetrating polymer network (semi-IPN). In this way, a photo-initiated radical click reaction was proposed to obtain a synthetic polymer, whose components were included in a CTS solution, resulting in the semi-IPN network after UV illumination. Different crosslinking degrees (CD) and CTS/polymer ratios were evaluated through rheological characterization, along with an assessment of both variables based on an experimental model design, obtaining that, for every CTS/polymer ratio, intermediate values of CD (8 %) offered the best rheological properties. In addition, chemical and microstructural characterization were carried out for selected hydrogels, obtaining consistent results according to rheological characterization, as the 1/1 CTS/polymer ratio with CD 8 % hydrogel displayed the most homogeneous pore size and distribution, consequently leading to the best rheological performance.},
organization = {This study was financially supported by MCIN/AEI/10.13039/5 01100011033/FEDER, UE, through the project PID2021-
124294OB-C21. The authors gratefully acknowledge their financial support. This work was also possible thanks to the postdoctoral contract of Víctor M. Pérez Puyana from the ‘‘Contratación de Personal Investigador Doctor” supported by the European Social Fund and Junta de Andalucía (PAIDI DOCTOR – Convocatoria 2019–2020, DOC_00586).},
publisher = {Elsevier},
title = {Chitosan-based hydrogels obtained via photoinitiated click polymer IPN reaction},
doi = {10.1016/j.molliq.2023.121735},
author = {Sánchez Cid, Pablo and Romero, Alberto and Díaz Blanco, Manuel Jesús and Paz Báñez, María Violante de and Pérez Puyana, Víctor},
}