@article{10272/22273,
year = {2023},
month = {1},
url = {https://hdl.handle.net/10272/22273},
abstract = {Diet is one of the most important modifiable lifestyle factors for preventing and
treating obesity. In this respect, the Mediterranean diet (MD) has proven to be a
rich source of a myriad of micronutrients with positive repercussions on human
health. Herein, we studied an observational cohort of children and adolescents with
obesity (N = 26) to explore the association between circulating blood trace elements
and the degree of MD adherence, as assessed through the KIDMED questionnaire.
Participants with higher MD adherence showed better glycemic/insulinemic control
and a healthier lipid profile, as well as raised plasma levels of selenium, zinc,
cobalt, molybdenum, and arsenic, and increased erythroid content of selenium.
Interestingly, we found that these MD-related mineral alterations were closely
correlated with the characteristic metabolic complications behind childhood obesity,
namely hyperglycemia, hyperinsulinemia, and dyslipidemia (p < 0.05, |r| > 0.35).
These findings highlight the pivotal role that dietary trace elements may play in the
pathogenesis of obesity and related disorders.},
organization = {This research was partially funded by the Spanish Government through Instituto de Salud Carlos III- (PI22/01899). ÁG-D
was supported by an intramural grant from the Biomedical Research and Innovation Institute of Cádiz (LII19/16INCO24),
and RG-D was recipient of a “Miguel Servet” fellowship (CP21/00120) funded by Instituto de Salud Carlos III.},
publisher = {Frontiers Media},
title = {Exploring the association between circulating trace elements, metabolic risk factors, and the adherence to a Mediterranean diet among children and adolescents with obesity},
doi = {10.3389/fpubh.2022.1016819},
author = {González Domínguez, Álvaro and Domínguez Riscart, Jesús and Millán Martínez, María and Lechuga Sancho, Alfonso María and González Domínguez, Raúl},
}