RT Journal Article
T1 Toward Light-Controlled Supramolecular Peptide Dimerization
A1 Fernandes, Rita J.
A1 Remón Ruiz, Patricia
A1 Moro, Artur J.
A1 Seco, André
A1 Ferreira, Ana S. D.
A1 Pischel, Uwe
A1 Basílio, Nuno
AB The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor−ligand complex with cucurbit[8]uril into a homoternary FGG2@CB8 assembly. The resulting lightinduced dimerization of the model peptide provides a tool for the implementation of stimuli-responsive supramolecular chemistry in biologically relevant contexts.
PB American Chemical Society
YR 2021
FD 2021-06-01
LK https://hdl.handle.net/10272/21354
UL https://hdl.handle.net/10272/21354
LA eng
NO Fernandes, R. J., Remón, P., Moro, A. J., Seco, A., Ferreira, A. S. D., Pischel, U., & Basílio, N. (2021). Toward Light-Controlled Supramolecular Peptide Dimerization. The Journal of Organic Chemistry, 86(12), 8472–8478. https://doi.org/10.1021/acs.joc.1c00464
NO The work was supported by the Associate Laboratory for Green ChemistryLAQV (UIDB/50006/2020) and by the Applied Molecular Biosciences UnitUCIBIO (UIDB/ 04378/2020), both financed by FCT. FCT/MCTES is also acknowledged for supporting the National Portuguese NMR Network (ROTEIRO/0031/2013-PINFRA/22161/2016, cofinanced by FEDER through COMPETE 2020, POCI, PORL, and FCT through PIDDAC) and for the grants PTDC/QUICOL/32351/2017, PTDC/QUI-QFI/30951/2017, and CEECIND/00466/2017 (N.B.). U.P. thanks the Spanish Ministry of Science, Innovation, and Universities (CTQ2017-89832-P). We are grateful to Dr. J.P. Da Silva for the mass spectrometry data (equipment financed by CRESC Algarve 2020 and COMPETE 2020; project EMBRC.PT ALG-01-0145-FEDER022121).Funding for open access charge: Universidad de Huelva / CBUA
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026