RT Journal Article
T1 Obesity- and Lipid-Related Parameters in the Identification of Older Adults with a High Risk of Prediabetes According to the American Diabetes Association: An Analysis of the 2015 Health, Well-Being, and Aging Study
A1 Ramírez Vélez, Robinson
A1 Pérez Sousa, Miguel Ángel
A1 González Ruíz, Katherine
A1 Cano Gutierrez, Carlos Alberto
AB This study evaluated the predictive ability of 11 obesity- and lipid-related parameters,including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WtHR), bodyroundness index (BRI), “A” body-shape index (ABSI), conicity index (C), visceral adiposity index(VAI), triglyceride-to-glucose fasting index (TyG), triglyceride-to-glucose fasting related to BMI(TyG-BMI), triglyceride-to-glucose fasting related to WC (TyG-WC), and triglyceride-to-glucosefasting related to WtHR (TyG-WtHR), to identify patients from an elderly Colombian population witha high risk of prediabetes according to the 2016 American Diabetes Association criteria. The datawere obtained from the 2015 Colombian Health and Wellbeing and Aging Survey. A total of 3307elderly Colombian individuals (aged over 60 years) were included. Anthropometric data, fastingplasma glucose, blood lipid profiles, family history, and health-related behaviors were assessed, andprediabetes was defined as a fasting plasma glucose of 100 to 125 mg/dL. The areas under the receiveroperating characteristic (ROC) curves (AUCs) were calculated for each anthropometric indicator,using the prediabetes classification to identify their sensitivity and specificity, and these indicated thatthe prevalence of prediabetes was 25.3% in this population. After adjusting for potential confoundingfactors, the TyG index was strongly associated with the odds of having prediabetes in both sexes,and multivariate logistic regression analysis showed that the ORs for prediabetes increased acrossquartiles (p < 0.001). The TyG index was best able to identify prediabetes in either sex (AUC andoptimal cut-o  = 0.700 and 8.72, and 0.695 and 8.92 for men and women, respectively), suggesting  that compared to the other parameters, the TyG index has the best discriminative power to predictprediabetes in the whole population. Thus, we propose the TyG index be used as a complementarymarker for assessing prediabetes in older adults.
PB MDPI
SN 2072-6643
YR 2019
FD 2019-11
LK http://hdl.handle.net/10272/17715
UL http://hdl.handle.net/10272/17715
LA eng
NO Ramírez-Vélez, R., Pérez Sousa, M. Á., González Ruíz, K. ...  Cano Gutiérrez, C. A.,(2019). Obesity- and Lipid-Related Parameters in the Identification of Older Adults with a High Risk of Prediabetes According to the American Diabetes Association: An Analysis of the 2015 Health, Well-Being, and Aging Study. Nutrients, 11(11), 2654. DOI: https://doi.org/10.3390/nu11112654
DS Repositorio Institucional de la Universidad de Huelva
RD 30 may 2026