RT Journal Article
T1 Fat–Fit Patterns, Drug Consumption, and Polypharmacy in Older Adults: The EXERNET Multi-Center Study
A1 Navarrete Villanueva, David
A1 Olivares Sánchez-Toledo, Pedro Rufino
A1 Casajús, José Antonio
AB Background: Physical fitness levels and the amount of accumulated adipose tissue (fatness)relate to current and future individuals’ heath status. Nevertheless, the interrelationships of theircombined patterns with polypharmacy and the types of medications consumed have not beensufficiently investigated. Methods: This cross-sectional study was carried out in six Spanish regionsbetween 2008 and 2009 with a sample of older community-dwelling adults (≥65 years old) withoutdementia or cancer. Fitness was measured with one-leg balance and senior fitness tests, as well as bymeasuring weight and fat mass with a bioelectrical impedance analyzer. Polypharmacy was definedas the use of five or more medications. An analysis of variance was performed for comparisonsbetween the physical fitness and fatness patterns and the medication consumed. Results: A total of1709 elders were included in the study (72.1 ± 5.2 years). The two unfit patterns were those with thehighest drug consumption. The High-Fat–Unfit pattern was the one that had the most significantconsumption and had the highest percentage of polymedicated subjects. The Low-Fat–Fit patternhad a significantly lower percentage of people that did not consume any medications. The highestpercentages of drug consumption in 7 of the 10 groups that were included were concentrated in thetwo unfit patterns. Conclusions: This study highlights the importance of fitness in older adults, as itis at least as important as the avoidance of accumulation of excess fat with respect to the consumptionof a smaller number of medicines.
PB MDPI
SN 2072-6643 (electrónico)
YR 2021
FD 2021
LK http://hdl.handle.net/10272/20455
UL http://hdl.handle.net/10272/20455
LA eng
NO Navarrete-Villanueva, D.; Gesteiro, E.; Gómez-Cabello, A.; Mañas, A.; Olivares, R.P.; Villa-Vicente, J.-G.; Gusi, N.; González-Gross, M.; Ara, I.; Vicente-Rodríguez, G.; Casajús, J.A. Fat–Fit Patterns, Drug Consumption, and Polypharmacy in Older Adults: The EXERNET Multi-Center Study. Nutrients 2021, 13, 2872. https://doi.org/10.3390/nu13082872
NO This research was funded by the Ministerio de Trabajo y Asuntos Sociales—IMSERSO(104/07), University of Zaragoza (UZ 2008-BIO-01), Ministerio de Sanidad, Servicios Sociales eIgualdad—IMSERSO (147/11), Centro Universitario de la Defensa de Zaragoza (UZCUD2016-BIO 01 and UZCUD2017-BIO-01), Ministerio de Educación y Ciencia (Red EXERNET DEP2005-00046),Biomedical Research Networking Center on Frailty and Healthy Aging (CIBERFES), BiomedicalResearch Networking Center on Pathophysiology of Obesity and Nutrition (CIBEROBN), FEDERfunds from the European Union (CB16/10/00477), and the 4IE+ project (0499_4IE_PLUS_4_E) fundedby the Interreg V-A España-Portugal (POCTEP) 2014–2020 program. In addition, D. N. received agrant from “Gobierno de Aragón” (DGAIIU/1/20).
DS Repositorio Institucional de la Universidad de Huelva
RD 1 jun 2026