RT Journal Article
T1 Diversion Colitis and Probiotic Stimulation: Effects of Bowel Stimulation Prior to Ileostomy Closure
A1 Rodríguez Padilla, Ángela
A1 Morales Martín, Germán
A1 Pérez Quintero, Rocío
A1 Rada Morgades, Ricardo
A1 Gómez Salgado, Juan
A1 Ruiz Frutos, Carlos
AB Background: Diversion colitis is a non-specific inflammation of a defunctionalisedsegment of the colon after a temporary stoma has been performed. This inflammation isassociated with a change in the colonic flora.Aim: To evaluate the efficacy and safety of preoperative stimulation of the efferentloop with probiotics prior to closure of the protective ileostomy in patients operatedon colorectal carcinoma and its effect on diversion colitis. A prospective, randomised,double-blind, controlled study is carried out.Methods: Patients who underwent surgery for colorectal carcinoma with protectiveileostomy pending reconstructive surgery and with diversion colitis as diagnosis areincluded. Randomised and divided into two groups. Histological and endoscopicchanges were evaluated after stimulation, after restorative surgery and during theshort-term follow-up after surgery.Results: Patients in CG were distributed according to the endoscopic index of severity inpre-stimulation/post-stimulation as follows: severe n = 9/9 (25.7%), moderate n = 23/23(65.7%), and mild n = 3/3 (8.6%); compared to the distribution in SG, severe n = 9/0(26.5/0%), moderate n = 23/3 (67.6/8.8%), mild n = 2/19 (5.9/55.9%) and normalcolonoscopy in 0/12 patients (0/35.3%).Conclusion: Probiotic stimulation of the efferent loop is a safe and effective method,managing to reduce both macroscopic and microscopic colitis, as well as a decrease insymptoms in the short term after reconstructive surgery.
PB Frontiers Media
SN 2296-858X (electrónico)
YR 2021
FD 2021-06
LK http://hdl.handle.net/10272/20081
UL http://hdl.handle.net/10272/20081
LA eng
NO Rodríguez-Padilla Á, Morales-Martín G, Pérez-Quintero R, Rada-Morgades R, Gómez-Salgado J and Ruiz-Frutos C (2021) Diversion Colitis and Probiotic Stimulation: Effects of Bowel Stimulation Prior to Ileostomy Closure. Front. Med. 8:654573. doi: 10.3389/fmed.2021.654573
DS Repositorio Institucional de la Universidad de Huelva
RD 31 may 2026