@article{10272/21161, year = {2022}, month = {3}, url = {http://hdl.handle.net/10272/21161}, abstract = {Replacement of fossil fuels has to be accompanied by the incorporation of bio-based procedures for the production of fine chemicals. With this aim, the microalga Chlamydomonas reinhardtii was selected for its ability to accumulate starch, an environmentally-friendly alternative source of chemical building blocks, such as 5′ -hydroxymethylfurfural or levulinic acid. The content of appreciated lipophilic coproducts was assessed in the selected microalga cultured at different nutritional conditions; and the parameters for the acidic hydrolysis of the algal biomass, obtained after pigments extraction, were optimized using a Central Composite Design. Response Surface Methodology predicted that the optimal hydrolysis conditions were elevated temperature, high DMSO % and short hydrolysis time for glucose. LA was favored at long times and high acid % and 5′ -HMF at lower acid % and high DMSO %. Chlamydomonas can therefore be used as a sustainable feedstock for the simultaneous production of high-added value lipophilic compounds and platform chemicals.}, organization = {Funding for open access charge: Universidad de Huelva / CBUA.}, publisher = {Elsevier}, title = {Simultaneous production of carotenoids and chemical building blocks precursors from chlorophyta microalgae}, doi = {10.1016/j.biortech.2022.127035}, author = {Rengel Domínguez, Rocío and Díaz Blanco, Manuel Jesús and Giráldez Díaz, Inmaculada and García Domínguez, María Trinidad and Vigara Fernández, Javier and León Bañares, Rosa María}, }