RT Journal Article
T1 Electrochemical oxidation of isothiazolinone biocides and their interaction with cysteine
A1 Ruiz Montoya, Mercedes
A1 Giráldez Díaz, Inmaculada
A1 Morales Carrillo de Albornoz, Emilio
A1 Estévez Brito, Rafael
A1 Rodríguez Mellado, José Miguel
AB This paper presents voltammetric studies on carbon electrodes (linear-sweep cyclic voltammetry and differencial pulse voltammetry) on the electrooxidation of methylisothiazolinone (MIT), Chloromethylisothiazolinone (CMIT) and 4,5-dichloro-2-octyl-4-isothiazolin-3-one (DCOIT). The oxidation products have been identified after electrolysis of the compounds using liquid-liquid extraction and gas chromatography coupled to mass spectrophotometry. The identified compounds for the three biocides correspond in all cases to two-electron processes, with opening of the ring. Adsorption processes were observed for CMIT. From the differential pulse voltammetric results a general reaction pathway is proposed in which the rate-determining step is a chemical reaction placed after the first partially irreversible electron transfer. The interaction of cysteine with MIT and CMIT was studied by differential pulse voltammetry in order to quantify them and the 1:3 mixture. The specificity of the interaction with cysteine and the low values of the peak potentials minimize the interferences. The quantification is made from the decrease of the oxidation signal of cysteine as the biocide concentration increases, being the method adequate for the study of usual cosmetic and household products.
PB Elsevier
SN 0013-4686
YR 2020
FD 2020
LK https://hdl.handle.net/10272/23477
UL https://hdl.handle.net/10272/23477
LA eng
NO Ruiz Montoya, M., Giráldez, I., Morales, E., Estévez Brito, R., & Rodríguez Mellado, J. M. (2020). Electrochemical oxidation of isothiazolinone biocides and their interaction with cysteine. In Electrochimica Acta (Vol. 337, p. 135770). Elsevier BV. https://doi.org/10.1016/j.electacta.2020.135770
NO Junta de Andalucía (Research Groups FQM-0198 and RNM371), Ministerio de Economía y Competitividad(research project CTQ-2015-68813R)
DS Repositorio Institucional de la Universidad de Huelva
RD 15 jun 2026