@article{10272/28457,
year = {2026},
url = {https://hdl.handle.net/10272/28457},
abstract = {The first orthogonal template strategy for the synthesis of higher order interlocked structures is described. Orthogonal cation and anion templates were employed in a stepwise fashion to construct a hetero[3] catenane composed of structurally distinct macrocyclic components. Importantly, the [3]catenane contains two interlocked binding cavities tailored for cation and anion binding, enabling it to function as a heteroditopic ion-pair receptor. The co-conformational dynamics and cation/anion binding properties of the [3]catenane were investigated by 1H NMR studies, which displayed temperature-dependent and guest-induced changes in chemical shift and linewidth. The potent ion-pair binding capability of the [3] catenane was confirmed by single-crystal X-ray diffraction studies, which showed the [3]catenane to recognise a sodium chloride ion-pair in a mechanically bonded receptor-separated ion-pair binding mode, wherein the two guest ions are encapsulated within their respective interlocked host cavities.},
organization = {H. M. T. acknowledges the Clarendon Fund and the Oxford Australia Scholarships Fund for a postgraduate research scholarship. A. D. would like to thank Gonville and Caius College, University of Cambridge for a Research Fellowship and funding. A. J. M.-M. acknowledges Financial support from the Spanish Ministerio de Ciencia, Innovación y Universidades MICIN/AEI/10.13039/501100011033 (PID2022-142270OB-I00), MICIN/NextGenerationEU/PRTR (CNS2022-136087), the European Research and Development Fund (ERDF) and the University of Huelva (EPIT1442023).},
publisher = {Royal Society of Chemistry},
title = {Orthogonal cation and anion template-directed synthesis of a heteroditopic [3]catenane for ionpair recognition},
doi = {10.1039/d5sc05942a},
author = {Tay, Hui Min and Docker, Andrew and Martínez Martínez, Antonio Jesús and Beer, Paul D.},
}