RT Journal Article
T1 Possible functional links among brain- and skull-related genes selected in modern humans
A1 Benítez Burraco, Antonio
A1 Boeckx, Cedric
AB The sequencing of the genomes from extinct hominins has revealed that changes in somebrain-related genes have been selected after the split between anatomically-modernhumans and Neanderthals/Denisovans. To date, no coherent view of these changes hasbeen provided. Following a line of research we initiated in Boeckx and Benítez-Burraco(2014a), we hypothesize functional links among most of these genes and their products,based on the existing literature for each of the gene discussed. The genes we focuson are found mutated in different cognitive disorders affecting modern populations andtheir products are involved in skull and brain morphology, and neural connectivity. Ifour hypothesis turns out to be on the right track, it means that the changes affectingmost of these proteins resulted in a more globular brain and ultimately brought aboutmodern cognition, with its characteristic generativity and capacity to form and exploitcross-modular concepts, properties most clearly manifested in language. [This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permission.]
PB Frontiers Media
SN 1664-302X
YR 2015
FD 2015
LK http://hdl.handle.net/10272/13532
UL http://hdl.handle.net/10272/13532
LA eng
NO Benítez Burraco, A., Boeckx, C.: "Possible functional links among brain- and skull-related genes selected in modern humans". Frontiers in Psychology. Vol. 6, art. 794, (2015). DOI: 10.3389/fpsyg.2015.00794
NO Preparation of this work was supported in part by funds from the Spanish Ministry of Economy and Competitiveness (grant number FPI-2013-43823-P), and by a Marie Curie International Reintegration Grant from the European Union (PIRG-GA-2009-256413). We wish to thank Constantina Theofanopoulou for providing comments, support and key information about some of the genes discussed above, which we would have missed otherwise. We are also grateful to the reviewers for an extremely insightful reading of the manuscript we submitted, which improved the paper considerably.
DS Repositorio Institucional de la Universidad de Huelva
RD 1 jun 2026