Maestre Cera, LourdesDorel, RuthPablo, ÓscarEscofet, ImmaSameera, W. M. C.Álvarez, EleuterioMaseras, FeliuDíaz Requejo, María MarEchavarren, Antonio M.Pérez Romero, Pedro José2019-04-252019-04-252017Maestre, L., Dorel, R., Pablo, Ó., Escofet, I., Sameera, W. M. C., Álvarez, E., … Pérez, P. J. (2017). Functional-Group-Tolerant, Silver-Catalyzed N–N Bond Formation by Nitrene Transfer to Amines. Journal of the American Chemical Society, 139(6), 2216-2223. https://doi.org/10.1021/jacs.6b082190002-78631520-5126http://hdl.handle.net/10272/16191Silver(I) promotes the highly chemoselective N-amidation of tertiary amines under catalytic conditions to form aminimides by nitrene transfer from PhI=NTs. Remarkably, this transformation proceeds in a selective manner in the presence of olefins and other functional groups without formation of the commonly observed aziridines or C-H insertion products. The methodology can be applied not only to rather simple tertiary amines but also to complex natural molecules such as brucine or quinine, where the products derived from N-N formation were exclusively formed. Theoretical mechanistic studies have shown that this selective Namidation reaction proceeds through triplet silver-nitrenes.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/CatalystAminimidesNitrenejournal article10.1021/jacs.6b08219open access