Casciotti, MartinaPérez Romero, Pedro JoséRodríguez Belderraín, TomásMuñoz Molina, José MaríaCasciotti2026-01-072026-01-072025-04-14Casciotti, M., Muñoz-Molina, J. M., Belderrain, T., & Perez, P. J. (2025). Efficient Synthesis of Amino Lactones via Copper‐catalysed Alkene Aminooxygenation. Advanced Synthesis & Catalysis, 367(11). https://doi.org/10.1002/adsc.202500062https://hdl.handle.net/10272/27605The synthesis of 5–7 membered oxygenated heterocycles by intramolecular aminooxygenation of unsaturated alkenes using commercially available N-fluorobenzenesulfonimide as amination reagent and TpiPr2Cu(NCCH3) as precatalyst is reported. With unsaturated aliphatic carboxylic acids, the corresponding lactones are obtained from moderate to almost quantitative yields employing a catalyst loading of 2.5 mol% under mild conditions, whereas 2-vinylbenzoic acids originate lower yields.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/AminationCopper catalysisRadical reactionsLactonesC-N bond formationjournal article10.1002/adsc.202500062open access