Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch

Basílio, NunoPischel, Uwe2018-04-202018-04-202016Basílio, N., Pischel, U.: "Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch". Chemistry - A European Journal. Vol. 22, págs. 15208–15211, (2016). DOI: 10.1002/chem.2016033310947-65391521-3765 (electrónico)http://hdl.handle.net/10272/14653The reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitchjournal article10.1002/chem.201603331open access