Muñoz Molina, José MaríaPérez Romero, Pedro José2019-10-032019-10-032019-05-27Muñoz Molina, J.M., Pérez Romero, P.J.: "Ruthenium-Catalyzed Heck-Type Alkenylation of Alkyl Bromides". Journal of Organic Chemistry. Vol. 84, 12, (2019). https://doi.org/10.1021/acs.joc.9b008980022-32631520-6904 (electrónico)http://hdl.handle.net/10272/16747The complex [Cp*RuCl(PPh3)2] displays a high catalytic activity for the Heck-type alkenylation of alkyl bromides, in the first example using this metal under thermal conditions. The coupling reaction proceeds efficiently with a variety of functionalized tertiary, secondary, and primary alkyl bromides. The presence of Hünig’s base has been revealed crucial for this transformation. Preliminary mechanistic studies support the participation of alkyl radicals in the reaction.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/Ruthenium catalysisAlkenylationCross-couplingSingle electron transferHomogeneous catalysisjournal article10.1021/acs.joc.9b00898open access