Ramírez Rodríguez, ManuelBeltrán Martín, ÁlvaroMudarra, Ángel L.Álvarez, EleuterioMaseras, FeliuDíaz Requejo, María MarPérez Romero, Pedro José2019-04-262019-04-262017Rodríguez, M. R., Beltrán, Á., Mudarra, Á. L., Álvarez, E., Maseras, F., Díaz-Requejo, M. M., & Pérez, P. J. (2017). Catalytic Nitrene Transfer To Alkynes: A Novel and Versatile Route for the Synthesis of Sulfinamides and Isothiazoles. Angewandte Chemie, 129(42), 13022–13027. https://doi.org/10.1002/ange.2017056641433-78511521-3773 electrónicohttp://hdl.handle.net/10272/16196A novel transformation is reported for the reaction of terminal or internal alkynes with the nitrene precursor PhI=NTs (Ts=p-toluenesulfonyl) in the presence of catalytic amounts of Tp(Br3)Cu(NCMe) (Tp(Br3)=hydrotris(3,4,5-tribromo-pyrazolylborate). Two products containing an imine functionality have been isolated from the reaction mixtures, identified as sulfinamides and isothiazoles. The former correspond to the formal reduction of the sulfone group into sulfoxide, whereas the latter involves the insertion of an alkyne carbon atom into the aromatic ring of the N-tosyl moiety.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/Alkyne functionalizationCopper catalysisIsothiazolesNitrene transferSulfinamidesjournal article10.1002/anie.201705664open access