Álvarez, MaríaMolina González, FranciscoRomero Fructos-Vázquez, ManuelUrbano Baena, JuanÁlvarez, EleuterioSodupe, MarionaLledós, AgustíPérez Romero, Pedro José2021-03-302021-03-302020-09Álvarez, M., Molina, F., Fructos, M. R., Urbano, J., Álvarez, E., Sodupe, M., Lledós, A., & Pérez, P. J. (2020). Aerobic intramolecular carbon–hydrogen bond oxidation promoted by Cu(i) complexes. Dalton Transactions, 49(41), 14647–14655. https://doi.org/10.1039/d0dt03198d1477-92261477-9234 (electrónico)http://hdl.handle.net/10272/19651The oxidation of C–H bonds by copper centres in enzymes with molecular oxygen takes place in nature under ambient conditions. Herein we report a similar transformation in which under ambient pressure and temperature (1 atm, 25 °C) the complex TpMsCu(THF) (TpMs = hydrotris(3-mesityl-pyrazol-1-yl)borate) undergoes the intramolecular oxidation of an alkylic C–H bond with O2, leading to the formation of a trinuclear compound where alkoxy and hydroxyl ligands are bonded to the copper centres, as inferred from X-ray studies. The presence of adventitious Cu(0) derived from the partial decomposition of initial TpMsCu(THF) facilitates the formation of such a trinuclear compound. DFT studies support the reaction taking place through a Cu(III) alkoxy-hydroxyl copper intermediate.engAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/journal article10.1039/d0dt03198dopen access23 Química