Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch
| dc.contributor.author | Basílio, Nuno | |
| dc.contributor.author | Pischel, Uwe | |
| dc.date.accessioned | 2018-04-20T09:45:10Z | |
| dc.date.available | 2018-04-20T09:45:10Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | The reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction. | es_ES |
| dc.description.center | CIQSO | |
| dc.description.department | Ingeniería Química, Química Física y Ciencias de los Materiales | |
| dc.description.sponsorship | This work was supported by the Spanish MINECO (grants CTQ2011-28390 and CTQ2014-54729-C2-1-P for U.P.), the Junta de Andalucia (grant P12-FQM-2140 for U.P.), the ERDF, the COST action CM1005 "Supramolecular Chemistry in Water", and the Associated Laboratory for Sustainable Chemistry-Clean Processes and Technologies-LAQV. The latter is financed by national funds from FCT/MEC (UID/QUI/50006/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265). The NMR equipment is part of The National NMR Facility, supported by the Portuguese FCT (RECI/BBB-BQB/0230/2012). N.B. gratefully acknowledges a post-doctoral grant from FCT/MEC (SFRH/BPD/84805/2012). N.B. also wishes to sincerely acknowledge Prof. Fernando Pina for his mentorship and generous support. | |
| dc.identifier.citation | Basílio, N., Pischel, U.: "Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch". Chemistry - A European Journal. Vol. 22, págs. 15208–15211, (2016). DOI: 10.1002/chem.201603331 | es_ES |
| dc.identifier.doi | 10.1002/chem.201603331 | |
| dc.identifier.issn | 0947-6539 | |
| dc.identifier.issn | 1521-3765 (electrónico) | |
| dc.identifier.uri | http://hdl.handle.net/10272/14653 | |
| dc.language.iso | eng | es_ES |
| dc.publisher | Wiley | es_ES |
| dc.relation.projectID | info:eu-repo/grantAgreement/Junta de Andalucia [P12-FQM-2140]info:eu-repo/grantAgreement/Spanish MINECO [CTQ2011-28390 CTQ2014-54729-C2-1-P] | |
| dc.relation.publisherversion | https://doi.org/10.1002/chem.201603331 | es_ES |
| dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
| dc.rights.accessRights | open access | es_ES |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
| dc.title | Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch | es_ES |
| dc.type | journal article | es_ES |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 167a3481-ecaf-42e1-b0e1-8fee1d243110 | |
| relation.isAuthorOfPublication.latestForDiscovery | 167a3481-ecaf-42e1-b0e1-8fee1d243110 |
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