Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch

dc.contributor.authorBasílio, Nuno
dc.contributor.authorPischel, Uwe
dc.date.accessioned2018-04-20T09:45:10Z
dc.date.available2018-04-20T09:45:10Z
dc.date.issued2016
dc.description.abstractThe reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.es_ES
dc.description.centerCIQSO
dc.description.departmentIngeniería Química, Química Física y Ciencias de los Materiales
dc.description.sponsorshipThis work was supported by the Spanish MINECO (grants CTQ2011-28390 and CTQ2014-54729-C2-1-P for U.P.), the Junta de Andalucia (grant P12-FQM-2140 for U.P.), the ERDF, the COST action CM1005 "Supramolecular Chemistry in Water", and the Associated Laboratory for Sustainable Chemistry-Clean Processes and Technologies-LAQV. The latter is financed by national funds from FCT/MEC (UID/QUI/50006/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265). The NMR equipment is part of The National NMR Facility, supported by the Portuguese FCT (RECI/BBB-BQB/0230/2012). N.B. gratefully acknowledges a post-doctoral grant from FCT/MEC (SFRH/BPD/84805/2012). N.B. also wishes to sincerely acknowledge Prof. Fernando Pina for his mentorship and generous support.
dc.identifier.citationBasílio, N., Pischel, U.: "Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch". Chemistry - A European Journal. Vol. 22, págs. 15208–15211, (2016). DOI: 10.1002/chem.201603331es_ES
dc.identifier.doi10.1002/chem.201603331
dc.identifier.issn0947-6539
dc.identifier.issn1521-3765 (electrónico)
dc.identifier.urihttp://hdl.handle.net/10272/14653
dc.language.isoenges_ES
dc.publisherWileyes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/Junta de Andalucia [P12-FQM-2140]info:eu-repo/grantAgreement/Spanish MINECO [CTQ2011-28390 CTQ2014-54729-C2-1-P]
dc.relation.publisherversionhttps://doi.org/10.1002/chem.201603331es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.accessRightsopen accesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.titleDrug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitches_ES
dc.typejournal articlees_ES
dspace.entity.typePublication
relation.isAuthorOfPublication167a3481-ecaf-42e1-b0e1-8fee1d243110
relation.isAuthorOfPublication.latestForDiscovery167a3481-ecaf-42e1-b0e1-8fee1d243110

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