Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch

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2016

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Ingeniería Química, Química Física y Ciencias de los Materiales

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CIQSO

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http://hdl.handle.net/10272/14653

DOI

10.1002/chem.201603331

Abstract

The reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.

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Basílio, N., Pischel, U.: "Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch". Chemistry - A European Journal. Vol. 22, págs. 15208–15211, (2016). DOI: 10.1002/chem.201603331

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