Toward Light-Controlled Supramolecular Peptide Dimerization

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dc.contributor.authorFernandes, Rita J.
dc.contributor.authorRemón Ruiz, Patricia
dc.contributor.authorMoro, Artur J.
dc.contributor.authorSeco, André
dc.contributor.authorFerreira, Ana S. D.
dc.contributor.authorPischel, Uwe
dc.contributor.authorBasílio, Nuno
dc.date.accessioned2022-12-13T13:30:08Z
dc.date.available2022-12-13T13:30:08Z
dc.date.issued2021-06-01
dc.description.abstractThe selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor−ligand complex with cucurbit[8]uril into a homoternary FGG2@CB8 assembly. The resulting lightinduced dimerization of the model peptide provides a tool for the implementation of stimuli-responsive supramolecular chemistry in biologically relevant contexts.es_ES
dc.description.departmentQuímica "Profesor José Carlos Vílchez Martín"
dc.description.sponsorshipThe work was supported by the Associate Laboratory for Green ChemistryLAQV (UIDB/50006/2020) and by the Applied Molecular Biosciences UnitUCIBIO (UIDB/ 04378/2020), both financed by FCT. FCT/MCTES is also acknowledged for supporting the National Portuguese NMR Network (ROTEIRO/0031/2013-PINFRA/22161/2016, cofinanced by FEDER through COMPETE 2020, POCI, PORL, and FCT through PIDDAC) and for the grants PTDC/QUICOL/32351/2017, PTDC/QUI-QFI/30951/2017, and CEECIND/00466/2017 (N.B.). U.P. thanks the Spanish Ministry of Science, Innovation, and Universities (CTQ2017-89832-P). We are grateful to Dr. J.P. Da Silva for the mass spectrometry data (equipment financed by CRESC Algarve 2020 and COMPETE 2020; project EMBRC.PT ALG-01-0145-FEDER022121). Funding for open access charge: Universidad de Huelva / CBUA
dc.identifier.citationFernandes, R. J., Remón, P., Moro, A. J., Seco, A., Ferreira, A. S. D., Pischel, U., & Basílio, N. (2021). Toward Light-Controlled Supramolecular Peptide Dimerization. The Journal of Organic Chemistry, 86(12), 8472–8478. https://doi.org/10.1021/acs.joc.1c00464
dc.identifier.doi10.1021/acs.joc.1c00464
dc.identifier.urihttps://hdl.handle.net/10272/21354
dc.language.isoenges_ES
dc.publisherAmerican Chemical Societyes_ES
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen accesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.otherDimerizationes_ES
dc.subject.otherIrradiationes_ES
dc.subject.otherLightes_ES
dc.subject.otherPeptides and Proteinses_ES
dc.subject.otherReceptorses_ES
dc.subject.unesco23 Químicaes_ES
dc.titleToward Light-Controlled Supramolecular Peptide Dimerizationes_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublication48a77d6a-af6c-4e1b-9e9a-65dbe12a6363
relation.isAuthorOfPublication167a3481-ecaf-42e1-b0e1-8fee1d243110
relation.isAuthorOfPublication.latestForDiscovery48a77d6a-af6c-4e1b-9e9a-65dbe12a6363

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