Ruthenium-Catalyzed Heck-Type Alkenylation of Alkyl Bromides

Thumbnail Image

Files

Ruthenium-Catalyzed.pdf (1.11 MB)

Publication date

2019-05-27

Authors

Advisors

Department

Química "Profesor José Carlos Vílchez Martín"

Research group

Center

CIQSO

Metrics

Google Scholar

Export

Research Projects

Organizational Units

Journal Issue

URI

http://hdl.handle.net/10272/16747

DOI

10.1021/acs.joc.9b00898

Abstract

The complex [Cp*RuCl(PPh3)2] displays a high catalytic activity for the Heck-type alkenylation of alkyl bromides, in the first example using this metal under thermal conditions. The coupling reaction proceeds efficiently with a variety of functionalized tertiary, secondary, and primary alkyl bromides. The presence of Hünig’s base has been revealed crucial for this transformation. Preliminary mechanistic studies support the participation of alkyl radicals in the reaction.

Keywords

Ruthenium catalysis; Alkenylation; Cross-coupling; Single electron transfer; Homogeneous catalysis

Unesco Subjects

Bibliographic citation

Muñoz Molina, J.M., Pérez Romero, P.J.: "Ruthenium-Catalyzed Heck-Type Alkenylation of Alkyl Bromides". Journal of Organic Chemistry. Vol. 84, 12, (2019). https://doi.org/10.1021/acs.joc.9b00898

Collections

Artículos
Atribución-NoComercial-SinDerivadas 3.0 España
The license for this item is described as Atribución-NoComercial-SinDerivadas 3.0 España